NAGS CLIA Kit for Human(Homo sapiens) | EIAab.comNAGS CLIA Kit for Human(Homo sapiens)

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Index > Protein center > NAGS(Gene name) > Human

NAGS (Gene name),

N-acetylglutamate synthase, mitochondrial (Protein name ), NAGS_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NAGS;

Protein name:

N-acetylglutamate synthase, mitochondrial;

Alternative:

Amino-acid acetyltransferase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Plays a role in the regulation of ureagenesis by producing variable amounts of N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.

Subcellular Location:

Mitochondrion matrix

Protein Attributes:

Sequence length:

534

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

534:

FWFGLADIRD | SYELVNHAKG | LPDSFHKPAS | DPGS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8N159

KEGG:

hsa:162417

MIM:

237310

Pfam:

PF04768

UniGene:

Hs.8876

STRING:

9606.ENSP00000293404

String:

Q8N159

Uniprot:

Q8N159

FOR

ELISA Kit for Human N-acetylglutamate synthase, mitochondrial

Cat.:

E15248m

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human N-acetylglutamate synthase, mitochondrial

Cat.:

E15248h

Price:

Please sign in first.

MSDS:

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Packing:

96T

CLIA Kit for Human N-acetylglutamate synthase, mitochondrial

Cat.:

U15248m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human N-acetylglutamate synthase, mitochondrial

Cat.:

U15248h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human N-acetylglutamate synthase, mitochondrial

Cat.:

P15248Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-acetylglutamate synthase, mitochondrial

Cat.:

P15248Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human N-acetylglutamate synthase, mitochondrial

Protein for Human N-acetylglutamate synthase, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mutation analysis in patients with N-acetylglutamate synthase deficiency."
Haeberle J. , Schmidt E. , Pauli S. , Kreuder J.G. , Plecko B. , Galler A. , Wermuth B. , Harms E. , Koch H.G.
Hum. Mutat.21:593-597(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY;VARIANTS NAGSD PRO-279; PRO-430 AND ARG-484
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Small intestine.
3.

"Cloning and expression of the human N-acetylglutamate synthase gene."
Caldovic L. , Morizono H. , Gracia Panglao M. , Gallegos R. , Yu X. , Shi D. , Malamy M.H. , Allewell N.M. , Tuchman M.
Biochem. Biophys. Res. Commun.299:581-586(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 94-534;ENZYME REGULATION;TISSUE SPECIFICITY
tissue: Liver.
4.

"Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms."
Zhao G. , Jin Z. , Allewell N.M. , Tuchman M. , Shi D.
PLoS ONE8:E70369-E70369(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 377-534 IN COMPLEX WITH N-ACETYL-GLUTAMATE;ENZYME REGULATION;SUBSTRATE-BINDING SITES;SUBUNIT;MUTAGENESIS OF TYR-441; ASN-479 AND TYR-485
5.

"Identification of novel mutations of the human N-acetylglutamate synthase gene and their functional investigation by expression studies."
Schmidt E. , Nuoffer J.-M. , Haeberle J. , Pauli S. , Guffon N. , Vianey-Saban C. , Wermuth B. , Koch H.G.
Biochim. Biophys. Acta1740:54-59(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NAGSD ARG-200; PRO-410; PRO-430; ARG-484 AND THR-518;CHARACTERIZATION OF VARIANTS NAGSD ARG-200; PRO-410; PRO-430; ARG-484 AND THR-518

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